PKA/C alpha/beta antibody (Cy7)
Quick Overview for PKA/C alpha/beta antibody (Cy7) (ABIN680099)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Predicted Reactivity
- Dog,Cow,Pig,Chicken
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PKA beta
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Isotype
- IgG
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anti-PKA/C alpha/beta (N-Term) antibody
Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Sheep WB, IF, IHC, IC Host: Rabbit Polyclonal unconjugated
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Application Notes
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Expiry Date
- 12 months
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- PKA/C alpha/beta
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Alternative Name
- Pka C Alpha+Beta
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Sub Type
- Cocktail
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Background
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Synonyms: PKA C beta, PKACB, PRKACB, Protein kinase cAMP dependent catalytic beta.
Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PKA beta (catalytic subunit) is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.
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Gene ID
- 81491
Target
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